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  • Monday to Saturday: 10 a.m. to 2:00 p.m.
  • Sunday: Closed

Holidays Closed:
New Years Day, Easter, Mother's Day, Memorial Day, Independence Day, Labor Day, Easter, Thanksgiving, Christmas

727 NE Greenwood Ave Bend OR 97701

  • Monday to Saturday: 10 a.m. to 2:00 p.m.
  • Sunday: Closed

Holidays Closed:
New Years Day, Easter, Mother's Day, Memorial Day, Independence Day, Labor Day, Easter, Thanksgiving, Christmas

Endocannaboid System

Did You Know Humans Have an  Endocannabinoid System?Human Endocannabinoid System

In the 1990’s, scientists discovered endocannabinoids, the natural cannabis-like molecules produced by the human body. Scientists began to realize cannabis exerted its effects, in part, by mimicking our endocannabinoids. It appears the main function of the endocannabinoid system is to maintain bodily homeostasis—biological harmony in response to changes in the environment.Taxonomic investigation revealed that the endocannabinoid system is incredibly old, having evolved over 500 million years ago. Moreover, it is present in all vertebrates—mammals, bird, reptiles, amphibians, fish, etc, all produce endocannabinoids!10 

Research initially suggested endocannabinoid receptors were only present in the brain and nerves, but scientists later found that the receptors are present throughout the body, including our skin, immune cells, bone, fat tissue, liver, pancreas, skeletal muscle, heart, blood vessels, kidney, and gastrointestinal tract.11 We now know the endocannabinoid system is involved in a wide variety of processes, including pain, memory, mood, appetite, stress, sleep, metabolism, immune function, and reproductive function.12,13 Endocannabinoids are arguably one of the most widespread and versatile signaling molecules known to man.

Content sourced from UCLAHealth.org

References

9. De Laurentiis A, Araujo HA, Rettori V. Role of the endocannabinoid system in the neuroendocrine responses to inflammation. Curr Pharm Des. 2014;20(29):4697-4706.

10. McPartland JM, Matias I, Di Marzo V, Glass M. Evolutionary origins of the endocannabinoid system. Gene. 2006;370:64-74.doi:https://doi.org/10.1016/j.gene.2005.11.004.

11. Mackie K. Cannabinoid receptors: where they are and what they do. J Neuroendocrinol. 2008;20 Suppl 1:10-14. doi:10.1111/j.1365-2826.2008.01671.x.

12. Alger BE. Getting High on the Endocannabinoid System. Cerebrum Dana Forum Brain Sci. 2013;2013.

13. Maccarrone M, Bab I, Bíró T, et al. Endocannabinoid signaling at the periphery: 50 years after THC. Trends Pharmacol Sci. 2015;36(5):277-296.doi:10.1016/j.tips.2015.02.008.

Disclaimer

The above statements have not been evaluated by the FDA. The information is for educational purposes only and is not intended to treat, cure, prevent or, diagnose any disease or condition. If a condition persists, contact your health care provider. WARNING: FOR EXTERNAL USE ONLY. KEEP OUT OF REACH OF CHILDREN CHECK WITH DOCTOR BEFOR USE IF PREGNANT.